Journal: Frontiers in Medical Technology
Article Title: Drug-loaded nanoparticles reduced platelet aggregation and blood coagulation
doi: 10.3389/fmedt.2025.1690389
Figure Lengend Snippet: Biocompatibility of anti-PLT LNPs. Light microscopy images of human fibroblasts cultured for 24 h with anti-PLT LNPs mixed with a growth medium at ratios of 0:1 (control), 0.5:1 (9.60 ± 0.09 × 10 −3 mol NO exposure), and 1:1 (19.20 ± 3.68 × 10 −3 mol NO exposure) show that cell population density in the 0.5:1 group was comparable to that in the control group. In contrast, a reduction in cell density was observed at the 1:1 ratio, consistent with the known antiproliferative effects of higher NO concentrations.
Article Snippet: The WI-38 human lung fibroblast cell line was purchased from ATCC (Manassas, VA, USA).
Techniques: Light Microscopy, Cell Culture, Control